• Remdesivir (GS-5734): Antiviral Nucleoside Analogue Workf...

  2025-10-19

  Remdesivir (GS-5734) is a benchmark antiviral nucleoside analogue for advanced coronavirus and Ebola virus research, offering potent, reproducible inhibition of viral RNA synthesis. This article delivers actionable protocols, workflow optimizations, and troubleshooting guidance, empowering researchers to harness Remdesivir’s unique mechanistic targeting of RNA-dependent RNA polymerase and exoribonuclease pathways.

• DRB (HIV Transcription Inhibitor): Unraveling RNA Polymer...

  2025-10-18

  Explore how 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB), a potent transcriptional elongation inhibitor, uniquely intersects with RNA polymerase II dynamics, cyclin-dependent kinase signaling, and cell fate transitions. This in-depth analysis reveals DRB's emerging roles in HIV, antiviral, and stem cell research beyond conventional perspectives.

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